Dermoscopic evaluation of extragenital lichen sclerosus et atrophicus
Keywords:
chrysalis like structure, comedo like openings, dermoscopy, extragenital lichen sclerosus, keratotic plugs, rosettes, white structureless areas.Abstract
Introduction: Lichen sclerosus (LS), is an uncommon inflammatory dermatosis with preferential involvement of anogenital region. Diagnosis of LS is mainly clinical, but clinical differentiation from conditions like vitiligo, morphea may be a difficult task at times that often requires histological analysis. Dermoscopy is one such non-invasive tool which can help diagnose the disease. There is paucity of Indian data on dermoscopy of LS.
Objectives: To evaluate clinical, dermatoscopic patterns of LS and correlate them with histopathology.
Methods: The study was conducted in a tertiary hospital after obtaining consent from 20 patients. OITEZ e-scope digital microscope was used to evaluate the lesions. Both polarized and nonpolarized mode were used and skin biopsy was done to confirm diagnosis.
Results: Based on morphology, LS was classified as scleroatrophic lesions (61.5%), guttate lesions (30.8%) and hyperkeratotic lesions (7.7%). Dermoscopic analysis revealed structureless white to yellow areas as most common finding (100%) followed by chrysalis like structure (80.8%). Linear irregular vessels were seen in 61.5% lesions and perifollicular scaling in 50.0% lesions. Keratotic plugs were seen in 50.0% lesions. A new characteristic finding, “rosettes” was seen in 38.5% lesions has never been reported with LS before. Non polarized mode was particularly useful for identifying texture changes, keratotic plugs and minute scales which were not visible otherwise.Conclusions: Dermoscopy is a simple diagnostic tool that helps in the early diagnosis of LS with specific pattern which can avoid invasive procedure like biopsy. Both non-polarised and polarized dermoscopy must be done to visualize the changes of LS well.
References
2. Meffert JJ, Davis BM, Grimwood RE. Lichen sclerosus. J Am Acad Dermatol. 1995;32(3):393–416.
3. Al-Refu K. Dermoscopy is a new diagnostic tool in diagnosis of common hypopigmented macular disease: a descriptive study. Dermatology Reports. 2018;
4. Marghoob AA, Cowell L, Kopf AW, Scope A. Observation of chrysalis structures with polarized dermoscopy. Arch Dermatol. 2009;145(5):618.
5. Ankad B, Beergouder S. Dermoscopic patterns in lichen sclerosus: A report of three cases. Indian Dermatol Online J. 2015;6(3):237.
6. Errichetti E, Lallas A, Apalla Z, Di Stefani A, Stinco G. Dermoscopy of Morphea and Cutaneous Lichen Sclerosus: Clinicopathological Correlation Study and Comparative Analysis. Dermatology. 2018;233(6):462–70.
7. Haspeslagh M, Noë M, De Wispelaere I, Degryse N, Vossaert K, Lanssens S, et al. Rosettes and other white shiny structures in polarized dermoscopy: Histological correlate and optical explanation. J Eur Acad Dermatol Venereol 2016;30:311-3.
8. Shim WH, Jwa SW, Song M, Kim HS, Ko HC, Kim MB, et al. Diagnostic usefulness of dermatoscopy in differentiating lichen sclerous et atrophicus from morphea. J Am Acad Dermatol [Internet]. 2012;66(4):690–1.
9. Liu J, Hao J, Liu Y, Lallas A. Dermoscopic features of lichen sclerosus in Asian patients: a prospective study. J Eur Acad Dermatol Venereol. 2020;34(11):e720-e721.
10. Larre Borges A, Tiodorovic-Zivkovic D, Lallas A, Moscarella E, Gurgitano S, Capurro M, et al. Clinical, dermoscopic and histopathologic features of genital and extragenital lichen sclerosus. J Eur Acad Dermatology Venereol. 2013;27(11):1433–9.
Published
Issue
Section
License
Copyright (c) 2022 Dr Sunanda Mahajan, Dr Jayati Dave

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.