Combined Use of Dermoscopy, Reflectance Confocal Microscopy, and Ex-Vivo Gene Expression Profiling to Detect a Micromelanoma Less Than 1 mm in Diameter

Combined Use of Dermoscopy, Reflectance Confocal Microscopy, and Ex-Vivo Gene Expression Profiling to Detect a Micromelanoma Less Than 1 mm in Diameter

Authors

  • Alexander Witkowski Department of Dermatology, Oregon Health and Sciences University, Portland, Oregon
  • Joanna Ludzik Department of Dermatology, Oregon Health and Sciences University, Portland, Oregon, United States; Department of Telemedicine and Bioinformatics, Jagiellonian University Medical College, Krakow, Poland
  • Jina Chung Department of Telemedicine and Bioinformatics, Jagiellonian University Medical College, Krakow, Poland
  • Claudia Lee Department of Dermatology, Oregon Health and Sciences University, Portland, Oregon
  • Sancy Leachman Department of Telemedicine and Bioinformatics, Jagiellonian University Medical College, Krakow, Poland
  • Giovanni Pellacani Department of Dermatology, La Sapienza University, Rome, Italy

Keywords:

reflectance confocal microscopy, dermoscopy, gene expression profiling, micro-melanoma, melanoma, skin cancer, early detection

References

Fried L, Tan A, Bajaj S, Liebman TN, Polsky D, Stein JA. Technological advances for the detection of melanoma: Advances in molecular techniques. J Am Acad Dermatol. 2020;83(4):996-1004. DOI:10.1016/j.jaad.2020.03.122. PMID: 32360759.

Saleh K. Dermoscopy of a Lentigo Maligna Less Than 1.5 mm in Diameter. Dermatol Pract Concept. 2021;11(2):e2021027. DOI: 10.5826/dpc.1102a27. PMID: 33747632. PMCID: PMC7943215.

Akay BN, Okcu Heper A, Clark S, et al. Dermatoscopy of a melanoma less than one millimeter in diameter. Int J Dermatol. 2017;56(12):1498-1499. DOI: 10.1111/ijd.13728. PMID: 28857145.

Regio Pereira A, Corral-Forteza M, Collgros H, et al. Dermoscopic features and screening strategies for the detection of small-diameter melanomas. Clin Exp Dermatol. 2022;47(5):932-941. DOI: 10.1111/ced.15094. PMID: 34997617. PMCID: PMC9546163.

Elmore JG, Barnhill RL, Elder DE, et al. Pathologists' diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study. BMJ. 2017;357:j2813. DOI: 10.1136/bmj.j2813. PMID: 28659278; PMCID: PMC5485913.

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Published

2023-01-31

Issue

Section

Research Letter

How to Cite

1.
Witkowski A, Ludzik J, Chung J, Lee C, Leachman S, Pellacani G. Combined Use of Dermoscopy, Reflectance Confocal Microscopy, and Ex-Vivo Gene Expression Profiling to Detect a Micromelanoma Less Than 1 mm in Diameter. Dermatol Pract Concept. 2023;13(1):e2023055. doi:10.5826/dpc.1301a55

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