Evaluation of Flexibility and Thickness of Cleft Lip Scars After Treatment with Microneedling Technique: a Cohort Trial
Keywords:
cleft lip, scar, scar management, scar treatment, microneedlingAbstract
Introduction:The early surgical treatment of the cleft lip led to a postoperative scar formation which may affect the physiological and psychological aspects of the patient.
Objectives: Evaluating the improvement rate of thescar flexibility and thickness of the cleft lip scar after treatment with the microneedling.
Methods: Sixteen patients (12 females and 4 males), aged 16-30 years who had a cleft lip scare were included in the current study.All patients suffered from a visible defective scar in the upper cleft lip.All patients were treated with a microneedling pen device combined with topical application of oil-based hyaluronic acid.The procedure was performed in 4 sessions with 3-week intervals between sessions.The scars were assessed by the patient and an external observer using the Patient and Observer Scar Assessment Scale.
Results:Thickness of the scar was improved according to the patient and observer opinions (67.28% and 61.55% respectively). Flexibility was improved according to the patient observer opinion (65.57% and 60.25% respectively).
Conclusions: Microneedling treatment can be considered as an effective method for the treatment of the defective scars resulting from the cleft lip plastic surgery.The microneedling technique is a simple,easy, safe, non-invasive, and low-cost procedure.
References
Silva HPVd, Arruda TTS, Souza KSCd, et al.: Risk factors and comorbidities in Brazilian patients with orofacial clefts. Braz Oral Res . 2018, 32:10.1590/1807-3107bor-2018.vol32.0024
Chen G, Li M-X, Wang H-X, et al.: Identification of key genes in cleft lip with or without cleft palate regulated by miR-199a-5p. Int J Pediatr Otorhinolaryngol . 2018, 111:128-137. 10.1016/j.ijporl.2018.06.005
de Korte CL, van Hees N, Lopata RG, Weijers G, Katsaros C, Thijssen JM: Quantitative assessment of oral orbicular muscle deformation after cleft lip reconstruction: an ultrasound elastography study. IEEE Trans Med Imaging . 2009, 28:1217-1222. 10.1109/TMI.2009.2013461
Soltani AM, Francis CS, Motamed A, et al.: Hypertrophic scarring in cleft lip repair: a comparison of incidence among ethnic groups. Clin Epidemiol . 2012, 4:187. 10.2147/CLEP.S31119
Baum CL, Arpey CJ: Normal cutaneous wound healing: clinical correlation with cellular and molecular events. Dermatol Surg . 2005, 31:674-686. 10.1111/j.1524-4725.2005.31612
Cohen M: Residual deformities after repair of clefts of the lip and palate. Clin Plast Surg . 2004, 31:331-345. 10.1016/S0094-1298(03)00133-0
Stal S, Hollier L: Correction of secondary cleft lip deformities. Plast Reconstr Surg. 2002, 109:1672-1681. 10.1097/00006534-200204150-00031
Zhang H, Deng F, Wang H, Huang Q, Zhang Y: Early orthodontic intervention followed by fixed appliance therapy in a patient with a severe Class III malocclusion and cleft lip and palate. Am J Orthod Dentofacial Orthop . 2013, 144:726-736. 10.1016/j.ajodo.2012.11.028
Monaco JL, Lawrence WT: Acute wound healing: an overview. Clin Plast Surg . 2003, 30:1-12. 10.1016/S0094-1298(02)00070-6
Van Zuijlen PP, Ruurda JJ, Van Veen HA, et al.: Collagen morphology in human skin and scar tissue: no adaptations in response to mechanical loading at joints. Burns. 2003, 29:423-431. 10.1016/S0305-4179(03)00052-4
Hu MS, Maan ZN, Wu J-C, et al.: Tissue engineering and regenerative repair in wound healing. Ann Biomed Eng . 2014, 42:1494-1507. 10.1007/s10439-014-1010-z
Amadeu TP, Braune AS, Porto LC, Desmoulière A, Costa AM: Fibrillin‐1 and elastin are differentially expressed in hypertrophic scars and keloids. Wound Repair Regen . 2004, 12:169-174. 10.1111/j.1067-1927.2004.012209.x
Watson D, Reuther MS: Scar revision techniques—pearls and pitfalls. Facial Plast Surg . 2012, 28:487-491. 10.1055/s-0032-1325642
Zhang C, Yin K, Shen Y-m: Efficacy of fractional carbon dioxide laser therapy for burn scars: a meta-analysis. J Dermatol Treat . 2021, 32:845-850. 10.1080/09546634.2019.1704679
Lima E, Lima M: PCI and Transcutaneous Drug Delivery. Percutaneous Collagen Induction With Microneedling. Springer, 2021185195.
Orentreich DS, Orentreich N: Subcutaneous incisionless (subcision) surgery for the correction of depressed scars and wrinkles. Dermatol Surg . 1995, 21:543-549.
Fearmonti R, Bond J, Erdmann D, Levinson H: A review of scar scales and scar measuring devices. Eplasty. 2010, 10:
Lakshmi YV, Reddy LS, Devi KNN, et al.: Evaluation of microneedling therapy in management of facial scars. J Craniofac Surg. 2020, 31:214-217. 10.1097/SCS.0000000000006145
El‐Domyati M, Barakat M, Awad S, Medhat W, El‐Fakahany H, Farag H: Multiple microneedling sessions for minimally invasive facial rejuvenation: an objective assessment. . Int J Dermatol. 2015, 54:1361-1369. 10.1111/ijd.12761
Lee HJ, Lee EG, Kang S, Sung J-H, Chung H-M, Kim DH: Efficacy of microneedling plus human stem cell conditioned medium for skin rejuvenation: a randomized, controlled, blinded split-face study. Ann Dermatol . 2014, 26:584-591. 10.5021/ad.2014.26.5.584
Aust MC, Fernandes D, Kolokythas P, Kaplan HM, Vogt PM: Percutaneous collagen induction therapy: an alternative treatment for scars, wrinkles, and skin laxity. Plast Reconstr Surg. 2008, 121:1421-1429. 10.1097/01.prs.0000304612.72899.02
Published
Issue
Section
License
Copyright (c) 2023 Mohamad Alghazawy, Yasser Almodalal
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.
