Functional Foods in Dermatology

Functional Foods in Dermatology

Authors

  • Emily Strouphauer Medical Student, Baylor College of Medicine
  • Milbrey Parke Department of Internal Medicine Resident, Tulane University School of Medicine
  • Ariadna Perez-Sanchez Department of Internal Medicine, University of Texas Health San Antonio
  • Evelyne Tantry Graduate, Rice University
  • Rajani Katta Clinical Professor of Dermatology, McGovern Medical School at UTHealth Houston

Keywords:

functional foods, diet, dermatology

Abstract

Functional foods, or whole foods that provide health benefits beyond their nutritional value, may provide multiple dermatological benefits. Research studies have documented benefits ranging from enhanced skin barrier function to improved wound healing, radiance, photoprotection, and hormonal regulation. Although the majority of research to date has involved small-scale human interventions or animal models, promising findings have been noted. In this review, we discuss the potential dermatological role of functional foods in hopes of advocating for larger-scale, evidence-based, human studies to expand this promising field.

References

Iizaka S, Nagata S, Sanada H. Nutritional status and habitual dietary intake are associated with frail skin conditions in community-dwelling older people. J Nutr Health Aging. 2017;21(2):137-146. doi:10.1007/s12603-016-0736-8

Katta R, Kramer MJ. Skin and Diet: An Update on the Role of Dietary Change as a Treatment Strategy for Skin Disease. Skin Ther Lett. 2018;23(1):1-5.

Hasler CM. Functional Foods: Benefits, Concerns and Challenges—A Position Paper from the American Council on Science and Health. J Nutr. 2002;132(12):3772-3781. doi:10.1093/jn/132.12.3772

Halsted CH. Dietary supplements and functional foods: 2 sides of a coin? Am J Clin Nutr. 2003;77(4):1001S-1007S. doi:10.1093/ajcn/77.4.1001S

Cho S. The Role of Functional Foods in Cutaneous Anti-aging. J Lifestyle Med. 2014;4(1):8-16. doi:10.15280/jlm.2014.4.1.8

Myriam M, Sabatier M, Steiling H, Williamson G. Skin bioavailability of dietary vitamin E, carotenoids, polyphenols, vitamin C, zinc and selenium. Br J Nutr. 2006;96(2):227-238. doi:10.1079/BJN20061817

Parrado C, Philips N, Gilaberte Y, Juarranz A, González S. Oral Photoprotection: Effective Agents and Potential Candidates. Front Med. 2018;5:188. doi:10.3389/fmed.2018.00188

Kanwar A. Skin barrier function. Indian J Med Res. 2018;147(1):117. doi:10.4103/0971-5916.232013

Strugar TL, Bs AK, Seité S, Lin M, Lio P. Connecting the Dots: From Skin Barrier Dysfunction to Allergic Sensitization, and the Role of Moisturizers in Repairing the Skin Barrier. 2019;18(6):6.

Akdeniz M, Gabriel S, Lichterfeld-Kottner A, Blume-Peytavi U, Kottner J. Transepidermal water loss in healthy adults: a systematic review and meta-analysis update. Br J Dermatol. 2018;179(5):1049-1055. doi:10.1111/bjd.17025

Spirt SD, Stahl W, Tronnier H, et al. Intervention with flaxseed and borage oil supplements modulates skin condition in women. Br J Nutr. 2008;101(3):440-445. doi:10.1017/S0007114508020321

Neukam K, De Spirt S, Stahl W, et al. Supplementation of flaxseed oil diminishes skin sensitivity and improves skin barrier function and condition. Skin Pharmacol Physiol. 2011;24(2):67-74. doi:10.1159/000321442

Boucetta KQ, Charrouf Z, Derouiche A, Rahali Y, Bensouda Y. Skin hydration in postmenopausal women: argan oil benefit with oral and/or topical use. Przegla̜d Menopauzalny Menopause Rev. 2014;13(5):280-288. doi:10.5114/pm.2014.46470

Callaway J, Schwab U, Harvima I, et al. Efficacy of dietary hempseed oil in patients with atopic dermatitis. J Dermatol Treat. 2005;16(2):87-94. doi:10.1080/09546630510035832

García-Burgos M, Moreno-Fernández J, Alférez MJM, Díaz-Castro J, López-Aliaga I. New perspectives in fermented dairy products and their health relevance. J Funct Foods. 2020;72:104059. doi:10.1016/j.jff.2020.104059

Kimoto-Nira H, Nagakura Y, Kodama C, et al. Effects of ingesting milk fermented by Lactococcus lactis H61 on skin health in young women: A randomized double-blind study. J Dairy Sci. 2014;97(9):5898-5903. doi:10.3168/jds.2014-7980

MORI N, KANO M, MASUOKA N, et al. Effect of probiotic and prebiotic fermented milk on skin and intestinal conditions in healthy young female students. Biosci Microbiota Food Health. 2016;35(3):105-112. doi:10.12938/bmfh.2015-022

KANO M, MASUOKA N, KAGA C, et al. Consecutive Intake of Fermented Milk Containing Bifidobacterium breve Strain Yakult and Galacto-oligosaccharides Benefits Skin Condition in Healthy Adult Women. Biosci Microbiota Food Health. 2013;32(1):33-39. doi:10.12938/bmfh.32.33

Isawa K, Noma T, Yamamoto M, et al. Verifying the Ability of Yogurt Prepared with LB81 Lactic Acid Bacteria to Improve Skin Function. 腸内細菌学雑誌. 2008;22:1-5. doi:10.11209/jim.22.1

Vaughn MG, Fu Q, Delisi M, et al. Prevalence and correlates of fire-setting in the United States: results from the National Epidemiological Survey on Alcohol and Related Conditions. Compr Psychiatry. 2010;51(3):217-223. doi:10.1016/j.comppsych.2009.06.002

Heinrich U, Moore CE, De Spirt S, Tronnier H, Stahl W. Green Tea Polyphenols Provide Photoprotection, Increase Microcirculation, and Modulate Skin Properties of Women. J Nutr. 2011;141(6):1202-1208. doi:10.3945/jn.110.136465

Ueda S, Tanahashi M, Higaki Y, Iwata K, Sugiyama Y. Ingestion of Coffee Polyphenols Improves a Scaly Skin Surface and the Recovery Rate of Skin Temperature after Cold Stress: A Randomized, Controlled Trial. J Nutr Sci Vitaminol (Tokyo). 2017;63(5):291-297. doi:10.3177/jnsv.63.291

Heinrich U, Neukam K, Tronnier H, Sies H, Stahl W. Long-Term Ingestion of High Flavanol Cocoa Provides Photoprotection against UV-Induced Erythema and Improves Skin Condition in Women. J Nutr. 2006;136(6):1565-1569. doi:10.1093/jn/136.6.1565

Kasuya A, Tokura Y. Attempts to accelerate wound healing. J Dermatol Sci. 2014;76(3):169-172. doi:10.1016/j.jdermsci.2014.11.001

Najmi M, Vahdat Shariatpanahi Z, Tolouei M, Amiri Z. Effect of oral olive oil on healing of 10-20% total body surface area burn wounds in hospitalized patients. Burns J Int Soc Burn Inj. 2015;41(3):493-496. doi:10.1016/j.burns.2014.08.010

Rosa A dos S, Bandeira LG, Monte-Alto-Costa A, Romana-Souza B. Supplementation with olive oil, but not fish oil, improves cutaneous wound healing in stressed mice. Wound Repair Regen. 2014;22(4):537-547. doi:10.1111/wrr.12191

Donato-Trancoso A, Monte-Alto-Costa A, Romana-Souza B. Olive oil-induced reduction of oxidative damage and inflammation promotes wound healing of pressure ulcers in mice. J Dermatol Sci. 2016;83(1):60-69. doi:10.1016/j.jdermsci.2016.03.012

Kwon AH, Qiu Z, Hashimoto M, Yamamoto K, Kimura T. Effects of medicinal mushroom (Sparassis crispa) on wound healing in streptozotocin-induced diabetic rats. Am J Surg. 2009;197(4):503-509. doi:10.1016/j.amjsurg.2007.11.021

Stephen ID, Coetzee V, Perrett DI. Carotenoid and melanin pigment coloration affect perceived human health. Evol Hum Behav. 2011;32(3):216-227. doi:10.1016/j.evolhumbehav.2010.09.003

Tan KW, Graf BA, Mitra SR, Stephen ID. Daily Consumption of a Fruit and Vegetable Smoothie Alters Facial Skin Color. PLOS ONE. 2015;10(7):e0133445. doi:10.1371/journal.pone.0133445

Darvin ME, Patzelt A, Knorr F, Blume-Peytavi U, Sterry W, Lademann J. One-year study on the variation of carotenoid antioxidant substances in living human skin: influence of dietary supplementation and stress factors. J Biomed Opt. 2008;13(4):044028. doi:10.1117/1.2952076

Whitehead RD, Re D, Xiao D, Ozakinci G, Perrett DI. You Are What You Eat: Within-Subject Increases in Fruit and Vegetable Consumption Confer Beneficial Skin-Color Changes. PLOS ONE. 2012;7(3):e32988. doi:10.1371/journal.pone.0032988

Rybak I, Carrington AE, Dhaliwal S, et al. Prospective Randomized Controlled Trial on the Effects of Almonds on Facial Wrinkles and Pigmentation. Nutrients. 2021;13(3):785. doi:10.3390/nu13030785

Henning SM, Guzman JB, Thames G, et al. Avocado Consumption Increased Skin Elasticity and Firmness in Women - A Pilot Study. J Cosmet Dermatol. 2022;21(9):4028-4034. doi:10.1111/jocd.14717

Fukushima Y, Takahashi Y, Hori Y, et al. Skin photoprotection and consumption of coffee and polyphenols in healthy middle-aged Japanese females. Int J Dermatol. 2015;54(4):410-418. doi:10.1111/ijd.12399

Latreille J, Kesse-Guyot E, Malvy D, et al. Dietary Monounsaturated Fatty Acids Intake and Risk of Skin Photoaging. Soyer HP, ed. PLoS ONE. 2012;7(9):e44490. doi:10.1371/journal.pone.0044490

Bosch R, Philips N, Suárez-Pérez J, et al. Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals. Antioxidants. 2015;4(2):248-268. doi:10.3390/antiox4020248

Number 2 SV 25. An Anti-Wrinkle Diet: Nutritional Strategies to Combat Oxidation, Inflammation and Glycation. Published March 15, 2020. Accessed October 26, 2022. https://www.skintherapyletter.com/aging-skin/anti-wrinkle-diet-nutritional-strategies-combat-oxidation-inflammation-glycation/

Katta R, Sanchez A, Tantry E. An Anti-Wrinkle Diet: Nutritional Strategies to Combat Oxidation, Inflammation and Glycation. Skin Ther Lett. 2020;25(2):3-7.

Katta R, Brown DN. Diet and Skin Cancer: The Potential Role of Dietary Antioxidants in Nonmelanoma Skin Cancer Prevention. J Skin Cancer. 2015;2015:893149. doi:10.1155/2015/893149

Heckman CJ, Chandler R, Kloss JD, et al. Minimal Erythema Dose (MED) Testing. J Vis Exp JoVE. 2013;(75):50175. doi:10.3791/50175

Stahl W, Heinrich U, Wiseman S, Eichler O, Sies H, Tronnier H. Dietary Tomato Paste Protects against Ultraviolet Light–Induced Erythema in Humans. J Nutr. 2001;131(5):1449-1451. doi:10.1093/jn/131.5.1449

Rizwan M, Rodriguez-Blanco I, Harbottle A, Birch-Machin M a., Watson R e. b., Rhodes L e. Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. Br J Dermatol. 2011;164(1):154-162. doi:10.1111/j.1365-2133.2010.10057.x

Williams S, Tamburic S, Lally C. Eating chocolate can significantly protect the skin from UV light. J Cosmet Dermatol. 2009;8(3):169-173. doi:10.1111/j.1473-2165.2009.00448.x

Mogollon JA, Boivin C, Lemieux S, Blanchet C, Claveau J, Dodin S. Chocolate flavanols and skin photoprotection: a parallel, double-blind, randomized clinical trial. Nutr J. 2014;13:66. doi:10.1186/1475-2891-13-66

Oak ASW, Shafi R, Elsayed M, et al. Dietary table grape protects against ultraviolet photodamage in humans: 1. clinical evaluation. J Am Acad Dermatol. 2021;85(4):1030-1032. doi:10.1016/j.jaad.2021.01.035

Oak ASW, Shafi R, Elsayed M, et al. Dietary table grape protects against ultraviolet photodamage in humans: 2. molecular biomarker studies. J Am Acad Dermatol. 2021;85(4):1032-1034. doi:10.1016/j.jaad.2021.01.036

Wang ZY, Huang MT, Lou YR, et al. Inhibitory effects of black tea, green tea, decaffeinated black tea, and decaffeinated green tea on ultraviolet B light-induced skin carcinogenesis in 7,12-dimethylbenz[a]anthracene-initiated SKH-1 mice. Cancer Res. 1994;54(13):3428-3435.

Riso P, Martini D, Møller P, et al. DNA damage and repair activity after broccoli intake in young healthy smokers. Mutagenesis. 2010;25(6):595-602. doi:10.1093/mutage/geq045

Hoelzl C, Glatt H, Meinl W, et al. Consumption of Brussels sprouts protects peripheral human lymphocytes against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and oxidative DNA-damage: results of a controlled human intervention trial. Mol Nutr Food Res. 2008;52(3):330-341. doi:10.1002/mnfr.200700406

Gill CI, Haldar S, Boyd LA, et al. Watercress supplementation in diet reduces lymphocyte DNA damage and alters blood antioxidant status in healthy adults. Am J Clin Nutr. 2007;85(2):504-510. doi:10.1093/ajcn/85.2.504

Riso P, Pinder A, Santangelo A, Porrini M. Does tomato consumption effectively increase the resistance of lymphocyte DNA to oxidative damage? Am J Clin Nutr. 1999;69(4):712-718. doi:10.1093/ajcn/69.4.712

Collins AR, Harrington V, Drew J, Melvin R. Nutritional modulation of DNA repair in a human intervention study. Carcinogenesis. 2003;24(3):511-515. doi:10.1093/carcin/24.3.511

Chai S, Davis K, Zhang Z, Zha L, Kirschner K. Effects of Tart Cherry Juice on Biomarkers of Inflammation and Oxidative Stress in Older Adults. Nutrients. 2019;11(2):228. doi:10.3390/nu11020228

Chen AC, Martin AJ, Choy B, et al. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention. N Engl J Med. 2015;373(17):1618-1626. doi:10.1056/NEJMoa1506197

Grant P. Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. a randomized controlled trial: SPEARMINT AND HIRSUTISM. Phytother Res. 2010;24(2):186-188. doi:10.1002/ptr.2900

Grant P, Ramasamy S. An Update on Plant Derived Anti-Androgens. Int J Endocrinol Metab. 2012;10(2):497-502. doi:10.5812/ijem.3644

Akdoğan M, Tamer MN, Cüre E, Cüre MC, Köroğlu BK, Delibaş N. Effect of spearmint (Mentha spicata Labiatae) teas on androgen levels in women with hirsutism. Phytother Res PTR. 2007;21(5):444-447. doi:10.1002/ptr.2074

Tehrani HG, Allahdadian M, Zarre F, Ranjbar H, Allahdadian F. Effect of green tea on metabolic and hormonal aspect of polycystic ovarian syndrome in overweight and obese women suffering from polycystic ovarian syndrome: A clinical trial. J Educ Health Promot. 2017;6:36. doi:10.4103/jehp.jehp_67_15

Armanini D, Mattarello MJ, Fiore C, et al. Licorice reduces serum testosterone in healthy women. Steroids. 2004;69(11-12):763-766. doi:10.1016/j.steroids.2004.09.005

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Published

2023-10-31

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Section

Review

How to Cite

1.
Functional Foods in Dermatology. Dermatol Pract Concept [Internet]. 2023 Oct. 31 [cited 2024 Sep. 10];13(4):e2023256. Available from: https://dpcj.org/index.php/dpc/article/view/3122

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