Successful Treatment of Pyoderma Gangrenosum With Composite Grafting of Acellular Dermal Matrix and Glycerolized Skin: A Preliminary Experience

Linda Tognetti; Laura  Calabrese; Elisa Pianigiani; Francesca Ierardi; Pietro Rubegni

doi:10.5826/dpc.1401a76

Successful Treatment of Pyoderma Gangrenosum With Composite Grafting of Acellular Dermal Matrix and Glycerolized Skin: A Preliminary Experience

Authors

Linda Tognetti Department of Dermatology, Division of Medical, Surgical and Neuro-Sciences, University of Siena, Siena (Italy) https://orcid.org/0000-0002-6691-4310
Laura Calabrese Dermatology Unit, Department of Medical, Surgical and Neurological Science, Dermatology Section, University of Siena, Siena, Italy
Elisa Pianigiani Skin Bank Unit, S. Maria alle Scotte Hospital, Siena, Italy
Francesca Ierardi Skin Bank Unit, S. Maria alle Scotte Hospital, Siena, Italy
Pietro Rubegni Dermatology Unit, Department of Medical, Surgical and Neurological Science, Dermatology Section, University of Siena, Siena, Italy

Keywords:

pyoderma gangrenosum, acellular dermis, ulceration, skin allograft

References

Maverakis E, Marzano AV, Le ST, et al. Pyoderma gangrenosum. Nature Reviews Disease Primers. 2020 Oct 8;6(1):81.

Pichler M, Thuile T, Gatscher B, et al. Systematic review of surgical treatment of pyoderma gangrenosum with negative pressure wound therapy or skin grafting. J Eur Acad Dermatol Venereol. 2017 Feb 1;31(2):e61-7.

Araújo FM, Kondo RN, Minelli L. Pyoderma gangrenosum: skin grafting and hyperbaric oxygen as adjuvants in the treatment of a deep and extensive ulcer. Anais brasileiros de dermatologia. 2013 Nov;88:176-8.

Tognetti L, DePiano E, Perotti R, et al. Clinical applications of skin Bank bioproducts. Technology in Practical Dermatology: Non-Invasive Imaging, Lasers and Ulcer Management. 2020:443-9.

Nita M, Pliszczyński J, Kowalewski C, et al. New treatment of wound healing with allogenic acellular human skin graft: preclinical assessment and in vitro study. InTransplantation Proceedings 2020 Sep 1 (Vol. 52, No. 7, pp. 2204-2207). Elsevier.

Tognetti L, Pianigiani E, Ierardi F, et al. The use of human acellular dermal matrices in advanced wound healing and surgical procedures: State of the art. Dermatologic Therapy. 2021 Jul;34(4):e14987.