Acne Keloidalis Nuchae: A Multicenter Retrospective Study of 142 Hispanic Patients
Keywords:
Acne Keloid, Folliculitis Keloidalis Nuchae, Hispanic or Latino, Follicular Occlusive DisordersAbstract
Introduction: Acne keloidalis nuchae (AKN) is a primary cicatricial alopecia with mixed infiltrate. It is more common in African or persons of African descent.
Objectives: Our objective was to describe the epidemiology and clinical and trichoscopic presentations of AKN in a large series of Hispanic patients.
Methods: This was a retrospective study from 10 different dermatological centers in Argentina, Colombia, Mexico, and Peru. Patients with a clinical diagnosis of AKN treated by 12 dermatologists experienced in trichology from 2018 to 2022 were included. The Umar classification system was used to determine severity.
Results: We identified 142 patients with AKN: 98% were male (n=140) with a mean age of 32 years; 108 patients had a previous history of trauma to the nuchal area (76%, p<0.001); and 48 were positive for a history of acne (33.8%, p=0.021). Patients with >50 months of evolution were mainly classified in classes III and IV compared to patients with an evolution of <50 months (30%, n=9 vs. 14%, n=15; p=0.019; respectively).
Conclusion: AKN should be considered in the differential diagnosis in the Hispanic population. Advanced stages of the disease are correlated with chronic evolution.
References
Ogunbiyi A. Acne keloidalis nuchae: prevalence, impact, and management challenges. Clin Cosmet Investig Dermatol. 2016;9:483-489. doi: 10.2147/CCID.S99225.
Adegbidi H, Atadokpede F, do Ango-Padonou F, Yedomon H. Keloid acne of the neck: epidemiological studies over 10 years. Int J Dermatol. 2005;44 Suppl 1:49-50. doi: 10.1111/j.1365-4632.2005.02815.x.
Maranda EL, Simmons BJ, Nguyen AH, Lim VM, Keri JE. Treatment of acne keloidalis nuchae: a systematic review of the literature. Dermatol Ther (Heidelb). 2016;6(3):363-78. doi: 10.1007/s13555-016-0134-5.
Shapero J, Shapero H. Acne keloidalis nuchae is scar and keloid formation secondary to mechanically induced folliculitis. J Cutan Med Surg. 2011;15(4):238-40. doi: 10.2310/7750.2011.10057.
Umar S, Lee DJ, Lullo JJ. A retrospective cohort study and clinical classification system of acne keloidalis nuchae. J Clin Aesthet Dermatol. 2021;14(4):E61-E67.
Loayza E, Vanegas E, Cherrez A, Cherrez Ojeda I. Acne keloidalis nuchae in Latin America: is there a different phenotype? Int J Dermatol. 2017;56(12):1469-1470. doi: 10.1111/ijd.13783.
Loayza E, Cazar T, Uraga V, Lubkov A, Garces JC. Acne keloidalis nuchae in Latin American women. Int J Dermatol. 2015;54(5):e183-5. doi: 10.1111/ijd.12092.
Kridin K, Solomon A, Tzur-Bitan D, Damiani G, Comaneshter D, Cohen AD. Acne keloidalis nuchae and the metabolic syndrome: a population-based study. Am J Clin Dermatol. 2020;21(5):733-739. doi: 10.1007/s40257-020-00541-z.
Matsunaga AM, Tortelly VD, Machado CJ, Pedrosa LR, Melo DF. High Frequency of Obesity in Acne Keloidalis Nuchae Patients: A Hypothesis from a Brazilian Study. Skin Appendage Disord. 2020 Nov;6(6):374-378. doi:10.1159/000509203.
East-Innis ADC, Stylianou K, Paolino A, Ho JD. Acne keloidalis nuchae: risk factors and associated disorders - a retrospective study. Int J Dermatol. 2017;56(8):828-832. doi: 10.1111/ijd.13678.
Na K, Oh SH, Kim SK. Acne keloidalis nuchae in Asian: A single institutional experience. PLoS One. 2017;12(12):e0189790. doi: 10.1371/journal.pone.0189790.
Lobato-Berezo A, Escolà-Rodríguez A, Courtney A, et al. Acne keloidalis nuchae: An international multicentric review of 79 patients. J Eur Acad Dermatol Venereol. 2023. doi: 10.1111/jdv.19609.
Chouk C, Litaiem N, Jones M, Zeglaoui F. Acne keloidalis nuchae: clinical and dermoscopic features. BMJ Case Rep. 2017;2017:bcr2017222222. doi: 10.1136/bcr-2017-222222.
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Copyright (c) 2024 Luis E. Sánchez-Dueñas, Mariana G. Ungson-García, Joel Alejandro Ramirez Sanchez, Ayala Barrera Antonio Michell , Marti Machado Miguel , Sonia Sofía Ocampo-Garza, Lizet K. Rojano-Fritz, Aldo Gálvez-Canseco, Lidia Elena Bernal López, Daniela Gutierrez Mendoza, Roxana Castañeda Yepiz, Araceli Alvarado Delgadillo, Yakelin Morales Miranda
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