Biologic Gray Zone of Melanocytic Tumors in Reality: Defining ‘Non-Conventional’ Melanocytic Tumors

Biologic Gray Zone of Melanocytic Tumors in Reality: Defining ‘Non-Conventional’ Melanocytic Tumors

Authors

  • Gerardo Ferrara Istituto Nazionale Tumori IRCCS Fondazione ‘G. Pascale’ – Naples, Italy
  • Alberto Gualandi Istituto Nazionale Tumori IRCCS Fondazione ‘G. Pascale’ – Naples, Italy
  • Nathalie Rizzo IRCCS Ospedale San Raffaele, Milan, Italy

Keywords:

nevus, melanocytoma, melanoma, histopathology, molecular genetics

References

Ferrara G, Argenyi Z, Argenziano G, et al. The influence of clinical information in the histopathologic diagnosis of melanocytic skin neoplasms. PlosONE (2009) 4,e5375.

Elder DE, Barnhil R, Bastian BC, et al. “Melanocytic tumour classification and the pathway concept” in (2018) WHO Classification of Skin Tumours, 4th Edition, eds. Elder D.E., Massi D., Scolyer R.A., Willemze R. (Lyon, F: IARC), pp. 66-71.

Ferrara G, Argenziano G. The WHO 2018 classification of cutaneous melanocytic neoplasms. Suggestion from routine practice. Front Oncol 2021;11:675296,

Ferrara G, Bradamante M. Melanocytic Skin Tumors: Does the molecular progression model fit with the routine clinicopathological practice? Dermatol Pract Concept 2019;10:e2020001

Lallas A, Kyrgidis A, Ferrara G, et al. Atypical Spitz tumours and sentinel lymph node biopsy: a systematic review. Lancet Oncol 2014: e178-e183.

Cancer Genome Atlas N. Genomic Classification of Cutaneous Melanoma. Cell 2015;161,1681-1696.

de la Fouchardiere A, Blokx W, van Kempen LC, Luzar B, et al. ESP, EORTC, and EURACAN Expert Opinion: practical recommendations for the pathological diagnosis and clinical management of intermediate melanocytic tumors and rare melanoma variants. Virch Arch 2021;479:3-11.

Pampena R, Kyrgidis A, Lallas A, Moscarella E, Argenziano G, Longo C. A meta-analysis of nevus-associated melanoma: Prevalence and practical implications. J Am Acad Dermatol 2017; 77:938-945

Zembowicz A, Carney JA, Mihm MC. Pigmented epithelioid melanocytoma: a low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevus. Am J Surg Pathol 2004;28:31-40.

Ferrara G, Rizzo N. Re: Molecular pathology as a diagnostic aid in difficult to classify melanocytic tumours with spitzoid morphology. Melanocytic tumors with Spitz-like morphology: toward a therapy-oriented diagnostic approach. Eur J Cancer 2021;157:511-513

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Published

2024-04-30

How to Cite

1.
Biologic Gray Zone of Melanocytic Tumors in Reality: Defining ‘Non-Conventional’ Melanocytic Tumors. Dermatol Pract Concept [Internet]. 2024 Apr. 30 [cited 2024 Sep. 10];14(2):e2024149. Available from: https://dpcj.org/index.php/dpc/article/view/4425

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