Hailey-Hailey disease associated with herpetic eczema—the value of the Tzanck smear test
Citation: Paulo Filho TA, deFreitas YK, da Nóbrega MT, Lima CB, Carriço BF, Leite Silva MA, Lauria Paulo F, Trindade Neto P. Hailey-Hailey disease associated with herpetic eczema—the value of the Tzanck smear test. Dermatol Pract Concept. 2014;4(4):4. http://dx.doi.org/10.5826/dpc.0404a04
Received: August 8, 2014; Accepted: September 11, 2014 ; Published: October 31, 2014
Copyright: ©2014 Paulo Filho et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Competing interests: The authors have no conflicts of interest to disclose.
All authors have contributed significantly to this publication.
Corresponding author: Thomas de Aquino Paulo Filho, M.D., 240, Deodoro Avenue, 59012600, Natal, RN, Brazil. Email: firstname.lastname@example.org
Background: Herpetic eczema is a herpetic superinfection of a preexisting skin disease. Hailey-Hailey disease is an autosomal dominant dermatosis that is clinically characterized by flaccid vesicles and rashes in intertriginous areas. The coexistence of those findings is a rare condition; only five cases have been published in literature.
Purpose: To report the rare coexistence between Hailey-Hailey disease and herpetic eczema and to highlight the importance of cytology for a quick diagnosis.
Case report: A 38-year-old man had been diagnosed with Hailey-Hailey disease for 13 years. His condition evolved into what could be herpetic eczema, which was later confirmed by skin cytology and histopathology. The man showed remission in the infection after 10 days under treatment with acyclovir.
Conclusion: Research on the concomitance of infection by the herpes virus must be performed in the exacerbations of Hailey-Hailey disease, and, in those situations, the quick diagnosis through skin cytology makes the early treatment possible.