Diffuse normolipemic plane xanthoma associated with monoclonal gammopathy

Yoon K. Cohen; David J. Elpern

doi:10.5826/dpc.0504a16

Diffuse normolipemic plane xanthoma associated with monoclonal gammopathy

Authors

Yoon K. Cohen
David J. Elpern The Skin Clinic, Williamstown, MA, USA

Keywords:

xanthoma, plane xanthoma, diffuse normolipemic plane xanthoma, multiple myeloma, lymphoproliferative disorder, monoclonal gammopathy, paraproteinemia

Abstract

Diffuse normolipemic plane xanthoma (DNPX) was first described by Altman and Winkelmann in 1962. It is a rare and non-inherited form of xanthomatosis. Clinically, the dermatosis is characterized by the presence of symmetric yellowish-orange plaques that favor the neck, upper trunk, flexural folds and periorbital region. It has been recognized to be associated with hematological diseases, especially with multiple myeloma and monoclonal gammopathy. We present a patient with diffuse plane xanthoma, normal lipid level, and monoclonal gammopathy.

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Published

2015-10-31

Issue

2015 Vol 5, No 4 | October

Section

Review

License

Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.

How to Cite

Cohen YK, Elpern DJ. Diffuse normolipemic plane xanthoma associated with monoclonal gammopathy. Dermatol Pract Concept. Published online October 31, 2015:65-67. doi:10.5826/dpc.0504a16