Effect of COVID-19 on Hair Diseases Observed by Health Care Providers: Analysis of 513 participants
Keywords:
COVID-19, hair diseases, surveys, questionnairesAbstract
Introduction: Covid-19 pandemic has been shown to have major acute and chronic impacts on the skin. Various studies, reported that there has been an increase in the number of patients who referred to the outpatient dermatology clinics with the complaint of variable hair diseases, during the era of Covid-19. Hair seems to be substantially affected by both the infection itself and anxiety/stress provoked by the pandemic. Therefore, understanding the impact of Covid-19 on the clinical course of variable hair diseases, has become a major concern in dermatology practice.
Objectives: To examine the frequency and types of various, both new-onset and ingravescent hair diseases observed in health care providers.
Methods: A web-based questionnaire related to the hair diseases seen in health care providers both prior to Covid-19 pandemic and after the start of the pandemic, was formed. The type of both new-onset and pre-existing hair diseases and ongoing hair diseases observed during Covid-19, were questioned.
Results: A total number of 513 participants were included in the study. One hundred seventy cases were diagnosed with Covid-19. During Covid-19 pandemic, 228 reported to have at least one hair disease; the most common one being telogen effluvium, followed by hair greying and seborrheic dermatitis. There was statistically significant relationship between the presence of a new-onset hair disease during the pandemic and being diagnosed with Covid-19 (p=0.004).
Conclusion: Our study shows that Covid-19 infection has a significant impact upon the emergence of new-onset hair diseases.
References
Daye M, Cihan FG, Durduran Y. Evaluation of skin problems and dermatology life quality index in health care workers who use personal protection measures during COVID-19 pandemic. Dermatol Ther. 2020;33(6):e14346. doi: 10.1111/dth.14346. PMID: 32985745; PMCID: PMC7536955.
Toncic RJ, Jakasa I, Hadzavdic SL, et al. Altered Levels of Sphingosine, Sphinganine and Their Ceramides in Atopic Dermatitis Are Related to Skin Barrier Function, Disease Severity and Local Cytokine Milieu. Int J Mol Sci. 2020;21(6):1958. doi: 10.3390/ijms21061958. PMID: 32183011; PMCID: PMC7139865.
Asghar F, Shamim N, Farooque U, Sheikh H, Aqeel R. Telogen Effluvium: A Review of the Literature. Cureus. 2020;12(5):e8320. doi: 10.7759/cureus.8320. PMID: 32607303; PMCID: PMC7320655.
Harland DP. Introduction to Hair Development. Adv Exp Med Biol. 2018;1054:89-96. doi: 10.1007/978-981-10-8195-8_8. PMID: 29797270.
Stenn KS, Paus R. Controls of hair follicle cycling. Physiol Rev. 2001;81(1):449-494. doi: 10.1152/physrev.2001.81.1.449. PMID: 11152763.
Rizzetto G, Diotallevi F, Campanati A, et al. Telogen effluvium related to post severe Sars-Cov-2 infection: Clinical aspects and our management experience. Dermatol Ther. 2021;34(1):e14547. doi: 10.1111/dth.14547. PMID: 33190397; PMCID: PMC7744849.
Abrantes TF, Artounian KA, Falsey R, et al. Time of onset and duration of post-COVID-19 acute telogen effluvium. J Am Acad Dermatol. 2021;85(4):975-976. doi: 10.1016/j.jaad.2021.07.021. PMID: 34302903; PMCID: PMC8294706.
FIvenson D. COVID-19: association with rapidly progressive forms of alopecia areata. Int J Dermatol. 2021;60(1):127. doi: 10.1111/ijd.15317. PMID: 33226118; PMCID: PMC7753616.
Öner Ü. Children with trichotillomania in COVID-19 outbreak. J Cosmet Dermatol. 2021;20(7):1967-1968. doi: 10.1111/jocd.14200. PMID: 33950551; PMCID: PMC8242538.
Alpalhão M, Gaibino N, Filipe P. Seborrheic dermatitis in COVID-19: a case report. Int J Dermatol. 2020;59(12):1543-1544. doi: 10.1111/ijd.15256. PMID: 33095515.
Mawhirt SL, Frankel D, Diaz AM. Cutaneous Manifestations in Adult Patients with COVID-19 and Dermatologic Conditions Related to the COVID-19 Pandemic in Health Care Workers. Curr Allergy Asthma Rep. 2020;20(12):75. doi: 10.1007/s11882-020-00974-w. PMID: 33047260; PMCID: PMC7549735.
Wilcha RJ. Does Wearing a Face Mask During the COVID-19 Pandemic Increase the Incidence of Dermatological Conditions in Health Care Workers? Narrative Literature Review. JMIR Dermatol. 2021;4(1):e22789. doi: 10.2196/22789. PMID: 34028470; PMCID: PMC8104277.
Rossi A, Magri F, Sernicola A, et al. Telogen Effluvium after SARS-CoV-2 Infection: A Series of Cases and Possible Pathogenetic Mechanisms. Skin Appendage Disord. 2021;21(5):1-5. doi: 10.1159/000517223. PMID: 34373830; PMCID: PMC8339054.
Rodríguez BO, Sánchez TL. The Psychosocial Impact of COVID-19 on health care workers. Int Braz J Urol. 2020;46(suppl.1):195-200. doi: 10.1590/S1677-5538.IBJU.2020.S124. PMID: 32618464; PMCID: PMC7719993.
Salazar de Pablo G, Vaquerizo-Serrano J, Catalan A, et al. Impact of coronavirus syndromes on physical and mental health of health care workers: Systematic review and meta-analysis. J Affect Disord. 2020;275:48-57. doi: 10.1016/j.jad.2020.06.022. PMID: 32658823; PMCID: PMC7314697.
Ibar C, Fortuna F, Gonzalez D, et al. Evaluation of stress, burnout and hair cortisol levels in health workers at a University Hospital during COVID-19 pandemic. Psychoneuroendocrinology. 2021;128:105213. doi: 10.1016/j.psyneuen.2021.105213. PMID: 33845387; PMCID: PMC8015376.
Di Landro A, Naldi L, Glaser E, Paus R, Tosti A. Pathobiology questions raised by telogen effluvium and trichodynia in COVID-19 patients. Exp Dermatol. 2021;30(7):999-1000. doi: 10.1111/exd.14352. PMID: 33838048; PMCID: PMC8250761.
Mieczkowska K, Deutsch A, Borok J, et al. Telogen effluvium: a sequela of COVID-19. Int J Dermatol. 2021;60(1):122-124. doi: 10.1111/ijd.15313. PMID: 33226117; PMCID: PMC7753411.
Cline A, Kazemi A, Moy J, Safai B, Marmon S. A surge in the incidence of telogen effluvium in minority predominant communities heavily impacted by COVID-19. J Am Acad Dermatol. 2021;84(3):773-775. doi: 10.1016/j.jaad.2020.11.032. PMID: 33310111.
Moreno-Arrones OM, Lobato-Berezo A, Gomez-Zubiaur A, et al. SARS-CoV-2-induced telogen effluvium: a multicentric study. J Eur Acad Dermatol Venereol. 2021;35(3):e181-e183. doi: 10.1111/jdv.17045. PMID: 33220124; PMCID: PMC7753386.
Rebora A. Trichodynia: a review of the literature. Int J Dermatol. 2016;55(4):382-4. doi: 10.1111/ijd.13204. PMID: 26696219.
Hussain N, Agarwala P, Iqbal K, et al. A systematic review of acute telogen effluvium, a harrowing post-COVID-19 manifestation. J Med Virol. 2022;94(4):1391-1401. doi: 10.1002/jmv.27534. PMID: 34931698.
Wambier CG, Goren A. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to be androgen mediated. J Am Acad Dermatol. 2020;83(1):308-309. doi: 10.1016/j.jaad.2020.04.032. PMID: 32283245; PMCID: PMC7151476.
Lee J, Yousaf A, Fang W, Kolodney MS. Male balding is a major risk factor for severe COVID-19. J Am Acad Dermatol. 2020;83(5):e353-e354. doi: 10.1016/j.jaad.2020.07.062. Erratum in: J Am Acad Dermatol. 2021 ;85(3):799. PMID: 32707256; PMCID: PMC7373684.
Goren A, Vaño-Galván S, Wambier CG, et al. A preliminary observation: Male pattern hair loss among hospitalized COVID-19 patients in Spain - A potential clue to the role of androgens in COVID-19 severity. J Cosmet Dermatol. 2020;19(7):1545-1547. doi: 10.1111/jocd.13443. PMID: 32301221.
Müller Ramos P, Ianhez M, Amante Miot H. Alopecia and grey hair are associated with COVID-19 Severity. Exp Dermatol. 2020;29(12):1250-1252. doi: 10.1111/exd.14220. PMID: 33098701.
Zhong J, Tang J, Ye C, Dong L. The immunology of COVID-19: is immune modulation an option for treatment? Lancet Rheumatol. 2020;2(7):e428-e436. doi: 10.1016/S2665-9913(20)30120-X. PMID: 32835246; PMCID: PMC7239618.
Rudnicka L, Rakowska A, Waskiel-Burnat A, Kurzeja M, Olszewska M. Mild-to-moderate COVID-19 is not associated with worsening of alopecia areata: A retrospective analysis of 32 patients. J Am Acad Dermatol. 2021;85(3):723-725. doi: 10.1016/j.jaad.2021.05.020. PMID: 34051315; PMCID: PMC8149466.
Rinaldi F, Trink A, Giuliani G, Pinto D. Italian Survey for the Evaluation of the Effects of Coronavirus Disease 2019 (COVID-19) Pandemic on Alopecia Areata Recurrence. Dermatol Ther (Heidelb). 2021;11(2):339-345. doi: 10.1007/s13555-021-00498-9. PMID: 33580408; PMCID: PMC7880634.
Veraldi S, Angileri L, Barbareschi M. Seborrheic dermatitis and anti-COVID-19 masks. J Cosmet Dermatol. 2020;19(10):2464-2465. doi: 10.1111/jocd.13669. PMID: 32790897; PMCID: PMC7436393.
Diefenbach GJ, Tolin DF, Hannan S, Crocetto J, Worhunsky P. Trichotillomania: impact on psychosocial functioning and quality of life. Behav Res Ther. 2005;43(7):869-84. doi: 10.1016/j.brat.2004.06.010. PMID: 15896284.
Pathoulas JT, Olson SJ, Idnani A, Farah RS, Hordinsky MK, Widge AS. Cross-sectional survey examining skin picking and hair pulling disorders during the COVID-19 pandemic. J Am Acad Dermatol. 2021;84(3):771-773. doi: 10.1016/j.jaad.2020.11.011.PMID: 33279648; PMCID: PMC7711196.
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