Assessment and Validity of Trichoscopy for Eyebrow Involvement in Lichen Planopilaris: A Case-Control Study

Assessment and Validity of Trichoscopy for Eyebrow Involvement in Lichen Planopilaris: A Case-Control Study

Authors

  • Awatef Kelati Dermatology Department, University Hospital Cheikh Khalifa, and the University Hospital Mohammed VI Faculty of Medicine, Mohammed VI University of Health and Sciences (UM6SS), Casablanca, Morocco
  • Wassim Halli Dermatology Department, University Hospital Cheikh Khalifa, and the University Hospital Mohammed VI Faculty of Medicine, Mohammed VI University of Health and Sciences (UM6SS), Casablanca, Morocco
  • Soumiya Chiheb Dermatology Department, University Hospital Cheikh Khalifa, and the University Hospital Mohammed VI Faculty of Medicine, Mohammed VI University of Health and Sciences (UM6SS), Casablanca, Morocco

Keywords:

Trichoscopy, Dermoscopy, Eyebrows, Hair disorders, Madarosis, Lichen planopilaris, Frontal fibrosing alopecia, Validity , Acquired eyebrow disorders

Abstract

Introduction: Few publications are available on eyebrow trichoscopy in patients with alopecia areata and frontal fibrosing alopecia (FFA).

Objective: We aimed to investigate the validity of using trichoscopy to examine the eyebrow involvement in patients with lichen planopilaris (LPP) and its variants.

Methods: In this case control study, 109 patients with eyebrow involvement in LPP and FFA (cases) and with acquired hair disorders of the eyebrows (controls) were included.

Results: Trichoscopy was highly specific and sensitive for the diagnosis of LPP and its variants, including FFA. Trichoscopic features significantly associated with LPP were peripilar scaling, peripilar pigmentation, broken hairs, peripilar white halos, diffuse empty follicles, and vellus hair. Localized peripilar erythema and empty follicles were significantly associated with the diffuse form of LPP and zigzag-type FFA. Yellow dots, dystrophic hairs, regrowth in different directions, and diffuse empty follicles were associated with LPP activity and FFA severity.

Conclusions: Trichoscopy is a valid tool for evaluating eyebrow involvement in LPP. Thus, it could help increase the diagnostic accuracy and predict the prognosis of eyebrow hair loss at an early stage.

References

Mumford BP, Eisman S, Yip L. Acquired causes of eyebrow and eyelash loss: A review and approach to diagnosis and treatment. Australas J Dermatol. févr 2023;64(1):28‑40.

Nguyen B, Hu JK, Tosti A. Eyebrow and Eyelash Alopecia: A Clinical Review. Am J Clin Dermatol. janv 2023;24(1):55‑67.

Suchonwanit P, Thammarucha S. Eyebrow growth pattern analysis in patients with eyebrow hypotrichosis after receiving topical treatment: A retrospective study. J Cosmet Dermatol. juin 2020;19(6):1404‑8.

Velez N, Khera P, English JC. Eyebrow loss: clinical review. Am J Clin Dermatol. 2007;8(6):337‑46.

Wyrwich KW, Kitchen H, Knight S, Aldhouse NVJ, Macey J, Nunes FP, et al. Development of Clinician-Reported Outcome (ClinRO) and Patient-Reported Outcome (PRO) Measures for Eyebrow, Eyelash and Nail Assessment in Alopecia Areata. Am J Clin Dermatol. oct 2020;21(5):725‑32.

Chiang C, Sah D, Cho BK, Ochoa BE, Price VH. Hydroxychloroquine and lichen planopilaris: Efficacy and introduction of Lichen Planopilaris Activity Index scoring system. J Am Acad Dermatol. 1 mars 2010;62(3):387‑92.

Vañó-Galván, S.; Molina-Ruiz, A.M.; Serrano-Falcón, C.; Arias-Santiago, S.; Rodrigues-Barata, A.R.; Garnacho-Saucedo, G.; Martorell-Calatayud, A.; Fernández-Crehuet, P.; Grimalt, R.; Aranegui, B.; et al. Frontal fibrosing alopecia: A multicenter review of 355 patients. J. Am. Acad. Dermatol. 2014, 70, 670–678.

Shakshouk H, Tosti A. Trichoscopy beyond scalp. A narrative review. Int J Dermatol. mars 2023;62(3):416‑27.

Fechine COC, Valente NYS, Romiti R. Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features. An Bras Dermatol. mai 2022;97(3):348‑57.

Starace M, Orlando G, Alessandrini A, Baraldi C, Bruni F, Piraccini BM. Diffuse variants of scalp lichen planopilaris: Clinical, trichoscopic, and histopathologic features of 40 patients. J Am Acad Dermatol. déc 2020;83(6):1659‑67.

Waśkiel-Burnat A, Rakowska A, Kurzeja M, Czuwara J, Sikora M, Olszewska M, et al. The value of dermoscopy in diagnosing eyebrow loss in patients with alopecia areata and frontal fibrosing alopecia. J Eur Acad Dermatol Venereol JEADV. janv 2019;33(1):213‑9.

Atış G, Sarı AŞ, Güneş P, Sönmez C. Isolated hair loss on the eyebrow: five cases with trichoscopic features. An Bras Dermatol. 2022;97(3):372‑5.

Chew AL, Bashir SJ, Wain EM, Fenton DA, Stefanato CM. Expanding the spectrum of frontal fibrosing alopecia: a unifying concept. J Am Acad Dermatol. oct 2010;63(4):653‑60.

Anzai A, Pirmez R, Vincenzi C, Fabbrocini G, Romiti R, Tosti A. Trichoscopy findings of frontal fibrosing alopecia on the eyebrows: A study of 151 cases. J Am Acad Dermatol. nov 2021;85(5):1130‑4.

Ferrari B, Vincenzi C, Tosti A. Pili Torti as a Sign of Eyebrow Involvement in Frontal Fibrosing Alopecia. Skin Appendage Disord. nov 2019;5(6):393‑5.

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Published

2024-10-30

How to Cite

1.
Assessment and Validity of Trichoscopy for Eyebrow Involvement in Lichen Planopilaris: A Case-Control Study. Dermatol Pract Concept [Internet]. 2024 Oct. 30 [cited 2024 Dec. 14];14(4):e2024277. Available from: https://dpcj.org/index.php/dpc/article/view/4692

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