Significant Nevi Regression Associated with Multiple Non-Metastatic Cutaneous Melanomas: A Case Report

Significant Nevi Regression Associated with Multiple Non-Metastatic Cutaneous Melanomas: A Case Report

Authors

  • Mislav Mokos University Hospital Center Sestre milosrdnice, Department of Dermatology and Venereology, Zagreb, Croatia https://orcid.org/0000-0001-9319-9255
  • Mirna Šitum University Hospital Center Sestre milosrdnice, Department of Dermatology and Venereology, Zagreb, Croatia, University of Zagreb School of Dental Medicine, Zagreb, Croatia, Croatian Academy of Sciences and Arts, Zagreb, Croatia
  • Davor Tomas University Hospital Center Sestre milosrdnice, Department of Pathology and Cytology, Zagreb, Croatia, University of Zagreb School of Medicine, Zagreb, Croatia
  • Sunčica Andrea Rogan Polyclinic Medikol, Zagreb, Croatia
  • Marija Buljan University Hospital Center Sestre milosrdnice, Department of Dermatology and Venereology, Zagreb, Croatia, University of Zagreb School of Dental Medicine, Zagreb, Croatia

Keywords:

nevi regression, melanoma, dermoscopy, Skin neoplasms, Case reports

References

Martín JM, Pinazo I, Monteagudo C, Markovic J, Allende A, Jordá E. Spontaneous Regression of Multiple Melanocytic Nevi After Melanoma: Report of 3 Cases. Am J Dermatopathol 2014; 36(11): e183-8. DOI: 10.1097/DAD.0000000000000033. PMID: 25343215.

Zindl CL, Chaplin DD. Immunology. Tumor immune evasion. Science 2010; 328(5979): 697-698. DOI: 10.1126/science.1190310. PMID: 20448171.

Farinazzo E, Zelin E, Agozzino M, et al. Regression of nevi, vitiligo-like depigmentation and halo phenomenon may indicate response to immunotherapy and targeted therapy in melanoma. Melanoma Res. 2021; 31(6): 582-5. DOI: 10.1097/CMR.0000000000000776. PMID: 34433200.

Speeckaert R, van Geel N, Luiten RM, et al. Melanocyte-specific immune response in a patient with multiple regressing nevi and a history of melanoma. Anticancer Res 2011; 31(11): 3697-703. PMID: 22110189.

Jaber NF, Paoli J, Jerkovic SG. Rapid regression of multiple melanocytic nevi in an individual with history of melanoma with the CDKN2A mutation. JAAD Case Rep 2023; 38: 113-6. DOI: 10.1016/j.jdcr.2023.06.019. PMID: 37484656.

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Published

2025-04-30

Issue

Vol. 15 No. 2 (2025): 2025 Vol 15, No 2 | April

Section

Research Letter

License

Copyright (c) 2025 Mislav Mokos, Mirna Šitum, Davor Tomas, Sunčica Andrea Rogan, Marija Buljan

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.

How to Cite

1.
Mokos M, Šitum M, Tomas D, Rogan SA, Buljan M. Significant Nevi Regression Associated with Multiple Non-Metastatic Cutaneous Melanomas: A Case Report. Dermatol Pract Concept. 2025;15(2):4912. doi:10.5826/dpc.1502a4912

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