Is Tunisian Endemic Pemphigus Foliaceus a Real Entity or Should These Cases Be Reclassified With Other Autoimmune Blistering Diseases?

Is Tunisian Endemic Pemphigus Foliaceus a Real Entity or Should These Cases Be Reclassified With Other Autoimmune Blistering Diseases?

Authors

Keywords:

Endemic pemphigus folaiceus, tunisian endemic pemphigus foliaceus, nososlogical classification

Author Biographies

Ana Maria Abreu-Velez, Georgia Dermatopathology Associates, Atlanta, Georgia, USA

Dr. Abreu has more than 28 years of health science, biomedical research and translational scientific experience involving human subjects with extended experience working in the fields, jungles with communities from the bench to the clinic and clinical trials to the formulation of programs-projects, protocols translating scientific discoveries into public health action in several areas. There is a great gap between the volume of scientific and public health knowledge generated through research and the application of that research in community settings. Dr. Abreu has been able to apply that knowledge by creating local, State, National and International projects, programs, booklets instructions, guidance working with patients, communities, health providers, community leaders, Shamans, private donors, and none-profit and for profit organizations and authorities in her field of expertise. She has applied those skills on a program of a new variant of endemic pemphigus foliaceus in El Bagre, Colombia, South America (Orphan diseases protected under The Orphan Drug Act law of 1983 of the United States) Also in programs to control and prevent sexual transmitted diseases, as well as in areas of high violence in inner cities cooperating with several religious group to decrease disease and violence Dr. Abreu leadership contributed to decrease the morbimortality in people affected by autoimmune blistering diseases from almost 97% of morbimortality to less than 3% working multidisciplinary. Dr. Abreu’s experienced in creating goals and objectives for a public health organization including the two larger Institutes of Tropical Diseases in Colombia at the University of Antioquia and at the Institute of Health Science, and as Director of Autoimmune and Blistering National Diseases Programs. Dr. Abreu scientific leadership is reflected in publications in peer-reviewed journals, including 100 first-authored papers (57 are now under PUBMED, 46 in review on Medline, 30 in preparation and 70 more in process of being added as a coauthor. Usually scientist at the highest international level rarely achieve more than 20 or 30 peer-reviewed journals as first authors in their entire productive scientific life. Dr. Abreu also had written a book and multiple book chapters. Dr. Abreu is often consulted in policy initiative and served as a national and/or international expert on public health science scientific research, private firms, governmental and none profit organizations. Dr. Abreu works alongside teams of people disseminating of evidence-based guidelines and effectively increasing awareness about several diseases. Dr. Abreu is considered a world leader in autoimmune skin blistering diseases and skin Immunodermatology and the leader in the study of a new variant of endemic pemphigus foliaceus (an orphan disease) the father of Immunodermatology Dr. Ernest H Beutner, PhD, whom died in recent years, gave her the torch of this field for her scientific and ethical services. This is quite an honor, coming from the person who discovered the autoimmune nature of pemphigus, pemphigoids, psoriasis, lupus band etc. For her groundbreaking achievements and break sin many dogmas in skin autoimmunity she is considered among the top in the world leaders in her research field. Dr. Abreu also discovered and characterized clinically, epidemiologically, immunological, genetically and environmentally new variant of endemic pemphigus foliaceus. She has also discovered new proteins, autoantigens, new junctions, and neural receptors/mechanoreceptors among many other accomplishments including developing of multiple complex immunological and molecular techniques. Dr. Abreu has more than 18 years of experience in management and leadership positions(s) that include administration, budget oversight, human resources management, liaison activities, and strategic leadership, publications in peer-reviewed journals, including 100 first-authored papers.  Dr. Abreu has knowledge of, or experience within managed care and health care settings and, more generally, a strong understanding of the business needs of complex organizations. Dr. Abreu has more than 28 years of experience as a scientist, physician-immunologist, dermatologist and expert in clinical trials, drug regulations tropical diseases and disease prevention. Dr. Abreu has more than 18 years in executive management; advising university presidents, boards of trustees, and advocates, as well as mentoring interns, pre-graduate students, fellows, physicians, scientist, PhD, post-doctoral fellows working multidisciplinary. Dr. Abreu has very high ethical standards. Dr. Abreu has led and overseen the implementation of several institutional long and short term goals in accordance with institutional strategies and risks, and managed these risks.

Willy Ramos MuNoz, Instituto de Investigaciones en Ciencias Biomédicas (INICIB). Universidad Ricardo Palma, Lima, Perú.

Dermatologist Instituto de Investigaciones en Ciencias Biomédicas (INICIB). Universidad Ricardo Palma, Lima, Perú.

Michael Howard, Georgia Dermatopathology Associates, Atlanta, GA, USA

President Georgia Dermatopahtology Associates, Atlanta, GA

References

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Digital 2024: Tunisia. Datareportal.com. Available from: https://datareportal.com/reports/digital-2024-tunisia#:~:text=Population%20of%20Tunisia%20in%202024,of%20the%20population%20is%20male. Accessed September 10, 2024.

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Published

2025-04-30

How to Cite

1.
Abreu-Velez AM, Ramos MuNoz W, Howard M. Is Tunisian Endemic Pemphigus Foliaceus a Real Entity or Should These Cases Be Reclassified With Other Autoimmune Blistering Diseases?. Dermatol Pract Concept. 2025;15(2):5008. doi:10.5826/dpc.1502a5008

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