Assessment of a Smartphone-Based Neural Network Application for the Risk Assessment of Skin Lesions under Real-World Conditions

Assessment of a Smartphone-Based Neural Network Application for the Risk Assessment of Skin Lesions under Real-World Conditions

Authors

  • Teresa Maria Kränke Department of Dermatology, Medical University of Graz, Austria https://orcid.org/0000-0001-8406-6063
  • Philipp Efferl Department of Dermatology and Venereology, Augenbruggerplatz 8 Medical University of Graz, Austria
  • Katharina Tripolt-Droschl Department of Dermatology and Venereology, Augenbruggerplatz 8 Medical University of Graz, Austria
  • Rainer Hofmann-Wellenhof Department of Dermatology and Venereology, Augenbruggerplatz 8 Medical University of Graz, Austria

Keywords:

Dermatology, Artificial Intelligence, Convolutional Neural Networks, skin lesion assessment, skin cancer

Abstract

Introduction: The diagnostic performance of convolutional neural networks (CNNs) in diagnosing different types of skin cancer has been quite promising. Mobile phone applications with integrated artificial intelligence (AI) are an understudied area.

Objective: We evaluated the risk assessment of the SkinScreener (Medaia GmbH, Graz, Austria) AI-based algorithm in comparison to an expert panel of 3 dermatologists.

Methods: In this retrospective single-center study at the Department of Dermatology and Venereology in Graz, photographs of lesions were taken by the users’ mobile phone cameras. The algorithm allocated them to 3 risk classes. Blinded to AI´s results, the images were evaluated by 3 dermatologists—our reference standard. A consensus was defined as at least a two-thirds majority.

Results: A total of 1,428 skin lesions were included. In 902 lesions (63.16%) there was a full agreement, and in 441 lesions (30.88%) a two-thirds majority was reached. Eighty-five lesions (5.69%) had to be discussed in a joint review process. The tested algorithm reached a sensitivity of 76.9% (CI 71.7%-81.5%) and a specificity of 80.9% (CI 78.5%-83.2%). Overall accuracy results were 77.2%.

Conclusions: Our results indicate that the tested mobile phone algorithm is a valuable tool for the correct risk classification of various skin lesions. As expected, its performance is worse than in a professional setting. Nonetheless, the use of these applications on mobile phones should raise awareness of skin cancer and encourage users to deal more intensively with preventive measures. In light of our results, these applications are also reliable for use by laypersons.

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Published

2025-07-31

How to Cite

1.
Kränke TM, Efferl P, Tripolt-Droschl K, Hofmann-Wellenhof R. Assessment of a Smartphone-Based Neural Network Application for the Risk Assessment of Skin Lesions under Real-World Conditions. Dermatol Pract Concept. 2025;15(3):5110. doi:10.5826/dpc.1503a5110

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