Hepatotoxicity Associated with Adalimumab in Hidradenitis Suppurativa: A Report of Two Cases of Drug-Induced Liver Injury

Cristian Fernando Caballero-Linares; Bianca Cei; Fernando Alfageme

doi:10.5826/dpc.1503a5320

Hepatotoxicity Associated with Adalimumab in Hidradenitis Suppurativa: A Report of Two Cases of Drug-Induced Liver Injury

Authors

Cristian Fernando Caballero-Linares Dermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain https://orcid.org/0009-0005-5652-7754
Bianca Cei Dermatology Department, University of Pisa, Italy https://orcid.org/0000-0002-9092-7795
Fernando Alfageme Dermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain https://orcid.org/0000-0002-7218-1598

Keywords:

Hidradenitis Suppurativa, Adalimumab, Drug-Induced Liver Injury (DILI), Hepatotoxicity.

References

Frider B, Bruno A, Ponte M, Amante M. Drug-induced liver injury caused by adalimumab: a case report and review of the bibliography. Case Reports Hepatol. 2013;2013:406901. DOI:10.1155/2013/406901. PMID: 25431703.

Kok B, Lester ELW, Lee WM, et al. Acute Liver Failure from Tumor Necrosis Factor-α Antagonists: Report of Four Cases and Literature Review. Dig Dis Sci. 2018;63(6):1654-1666. DOI:10.1007/s10620-018-5023-6. PMID: 29564668.

French JB, Bonacini M, Ghabril M, Foureau D, Bonkovsky HL. Hepatotoxicity Associated with the Use of Anti-TNF-α Agents. Drug Saf. 2016;39(3):199-208. DOI:10.1007/s40264-015-0366-9. PMID: 26692395

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Published

2025-07-31

Issue

Vol. 15 No. 3 (2025): 2025 Vol 15, No 3 | July

Section

Research Letter

License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.

How to Cite

Caballero-Linares CF, Cei B, Alfageme F. Hepatotoxicity Associated with Adalimumab in Hidradenitis Suppurativa: A Report of Two Cases of Drug-Induced Liver Injury. Dermatol Pract Concept. 2025;15(3):5320. doi:10.5826/dpc.1503a5320