The Effect of Dupilumab on Growth Parameters in Pediatric Atopic Dermatitis Patients

Vincenzo Piccolo; Teresa Russo; Julia Nowowiejska; Giuseppe Argenziano; Carlo Mazzatenta; Andrea Bassi

doi:10.5826/dpc.1503a5420

The Effect of Dupilumab on Growth Parameters in Pediatric Atopic Dermatitis Patients

Authors

Vincenzo Piccolo Dermatology Unit, University of Campania “Luigi Vanvitelli”, Naples, Italy
Teresa Russo Dermatology Unit, University of Campania “Luigi Vanvitelli”, Naples, Italy
Julia Nowowiejska Department of Dermatology and Venereology, Medical University of Bialystok, Bialystok, Poland
Giuseppe Argenziano Dermatology Unit, University of Campania “Luigi Vanvitelli”, Naples, Italy
Carlo Mazzatenta Division of Dermatology, Azienda USL Toscana Nord Ovest, Lucca, Italy
Andrea Bassi Division of Dermatology, Azienda USL Toscana Nord Ovest, Lucca, Italy

Keywords:

Atopic dermatitis, Eczema, Dupilumab, Growth, Height

References

Paller AS, Siegfried EC, Thaçi D, et al. Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: A randomized, double-blinded, placebo-controlled phase 3 trial. J Am Acad Dermatol. 2020;83(5):1282-1293. PMID: 32574587, DOI: 10.1016/j.jaad.2020.06.054.

Patruno C, Fabbrocini G, Lauletta G, et al. A 52-week multicenter retrospective real-world study on effectiveness and safety of dupilumab in children with atopic dermatitis aged from 6 to 11 years. J Dermatolog Treat. 2023;34(1):2246602. PMID: 37580895 DOI: 10.1080/09546634.2023.2246602.

Napolitano M, Fabbrocini G, Neri I, et al. Dupilumab Treatment in Children Aged 6-11 Years With Atopic Dermatitis: A Multicentre, Real-Life Study. Paediatr Drugs. 2022;24(6):671-678. PMID: 36028611 PMCID: PMC9417930 DOI: 10.1007/s40272-022-00531-0.

Zhang M, He M, Tang T. The effect of atopic dermatitis in pediatric patients on height: Reflections triggered by a real-life case report. Medicine (Baltimore). 2023;102(47):e36150. PMID: 38013381 PMCID: PMC10681620 DOI: 10.1097/MD.0000000000036150.

Paller AS, Geng B, Irvine A, et al. Growth Analysis in Children Aged Less Than 12 Years with Moderate-to-Severe Atopic Dermatitis. Paper presented: American Academy of Dermatology (AAD) 2024 Annual Meeting. March 8 – 12, 2024. San Diego, CA. https://aad-eposters.s3.amazonaws.com/AM2024/poster/51363/Growth+Analysis+in+Children+Aged+Less+Than+12+Years+with+Moderate-to-Severe+Atopic+Dermatitis.pdf. Accessed December 16, 2024.

Irvine A, Paller A, Horowitz J, et al. Dupilumab Treatment of Children With Atopic Dermatitis Increases Bone Alkaline Phosphatase, Regardless Of Asthma Comorbidity. Ann Allergy, Asthma Immunol. 2023; 131 (5-Suppl 1): S11. DOI: 10.1016/j.anai.2023.08.048