Factors Associated with Exacerbation in Psoriasis compared to Eczema

Thanaphon  Anutraungkool; Suteeraporn Chaowattanapanit; Charoen Choonhakarn; Panita Limpawattana; Narachai Julanon; Rachot Wongjirattikarn; Krauwan  Kruahong; Anongnit  Mokkarat; Kittisak Sawanyawisuth

doi:10.5826/dpc.1504a5630

Factors Associated with Exacerbation in Psoriasis compared to Eczema

Authors

Thanaphon Anutraungkool Division of Dermatology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
Suteeraporn Chaowattanapanit Division of Dermatology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
Charoen Choonhakarn Division of Dermatology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
Panita Limpawattana Division Geriatric Medicine, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
Narachai Julanon Division of Dermatology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
Rachot Wongjirattikarn Division of Dermatology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
Krauwan Kruahong Outpatient Department, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Anongnit Mokkarat Outpatient Department, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Kittisak Sawanyawisuth Ambulatory Medicine, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand

Keywords:

psoriasis , eczema, Aggravation, exacerbation

Abstract

Introduction: Psoriasis and eczema are chronic inflammatory skin diseases. Environmental factors play an important role in the pathogenesis and exacerbation of both conditions.

Objective: This study aimed to investigate factors associated with exacerbation in psoriasis and eczema and compare those factors between both diseases, with the aim of identifying the significant differences between the two conditions.

Methods: A cross-sectional study was conducted on adult patients diagnosed with psoriasis and eczema. Demographic characteristics, clinical data, and aggravating factors were collected and compared between both groups. Demographic characteristics and clinical data were analyzed using descriptive statistics, while aggravating factors were analyzed by regression analysis.

Results: A total of 280 patients participated in this study: 192 psoriasis patients and 88 eczema patients. In 97.3% of psoriasis patients and 99.7% of eczema patients, aggravating factors were reported during disease exacerbation. Mental stress and inadequate sleep were significantly associated with psoriasis exacerbation, while humid environment and dust were significantly associated with eczema exacerbation rather than psoriasis exacerbation.

Conclusion: Internal factors, such as mental stress and inadequate sleep, have a greater influence on the worsening of psoriasis, whereas external factors, including humid environment and dust, have a more significant impact on eczema flare-ups than on psoriasis exacerbation.

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