Cutaneous and orbital myeloid sarcoma as the initial clinical presentation of acute myeloid leukemia in an infant.

Leonne Di Carlo Del Vecchio; Jan Lapins; Elizabeth Leocadia Fernandes; Marcia Lanzoni de Alvarenga Lira; Fernanda Magalhães; Meliane Moleta

doi:10.5826/dpc.1504a5858

Cutaneous and orbital myeloid sarcoma as the initial clinical presentation of acute myeloid leukemia in an infant.

Authors

Leonne Di Carlo Del Vecchio Department of Dermatology, Taubaté University Hospital, Taubaté - São Paulo, Brazil
Jan Lapins Karolinska University Hospital and Karolinska Institutet
Elizabeth Leocadia Fernandes Department of Dermatology, Taubaté University Hospital
Marcia Lanzoni de Alvarenga Lira Department of Dermatology, Taubaté University Hospital
Fernanda Magalhães Department of Dermatology, Taubaté University Hospital, Taubaté - São Paulo, Brazil
Meliane Moleta Department of Dermatology, Mogi das Cruzes University, Mogi das Cruzes - São Paulo, Brazil

Keywords:

Acute Myeloid Leukemia, Cutaneous Myeloid Sarcoma, Chloroma, Granulocytic sarcoma, Pediatric leukemia, Dermoscopy

References

Vasconcelos ERA, Bauk AR, Rochael MC. Cutaneous myeloid sarcoma associated with chronic myeloid leukemia. An Bras Dermatol. 2017;92(5 Suppl 1):50-52. DOI: 10.1590/abd1806-4841.20176042.

Xu LH, Wang Y, Chen ZY, Fang JP. Myeloid sarcoma is associated with poor clinical outcome in pediatric patients with acute myeloid leukemia. J Cancer Res Clin Oncol. 2020;146(4):1011-1020. DOI:10.1007/s00432-020-03128-7

Lo WP, Kuo CH, Kuo MT, Fang PC. Isolated conjunctival myeloid sarcoma as a presenting sign of acute leukemia. Chang Gung Med J. 2010;33(4):334-337.

Raja V, Bryant B, Bessman DJ, Alperin JB. Granulocytic sarcoma: presentation with nodal and skin involvement. J Clin Oncol. 2004;22(10):2026-2027. DOI:10.1200/JCO.2004.06.103

de Arruda Câmara VM, Morais JC, Portugal R, da Silva Carneiro SC, Ramos-e-Silva M. Cutaneous granulocytic sarcoma in myelodysplastic syndrome. J Cutan Pathol. 2008;35(9):876-879. DOI:10.1111/j.1600-0560.2007.00916.x

Sławińska M, et al. Dermoscopic features of leukemia cutis: case series. Indian J Dermatol. 2021;66(2):187-190. DOI:10.4103/ijd.IJD_534_19.

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Published

2025-10-31

Issue

Vol. 15 No. 4 (2025): 2025 Vol 15, No 4 | October

Section

Research Letter

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How to Cite

Di Carlo Del Vecchio L, Jan Lapins, Elizabeth Leocadia Fernandes, Marcia Lanzoni de Alvarenga Lira, Fernanda Magalhães, Meliane Moleta. Cutaneous and orbital myeloid sarcoma as the initial clinical presentation of acute myeloid leukemia in an infant. Dermatol Pract Concept. 2025;15(4):5858. doi:10.5826/dpc.1504a5858