Pigmented tumor in the nostril
Keywords:
inverted follicular keratosis, seborrheic keratosisAbstract
A 64-year-old man was noted to have a single pigmented lesion in the nostril of his nose. Clinical examination revealed a 5 mm nodular growth and brown lesion. With a presumed clinical diagnosis of malignant skin tumor, a biopsy was performed. The histological examination revealed the unexpected diagnosis of pigmented inverted follicular keratosis.
The inverted follicular keratosis is an uncommon benign lesion that is usually diagnosed histologically rather than clinically. It commonly simulates other proliferative skin lesions.
References
2. Adrian J. Inverted follicular keratosis of the lip. Oral Surg Oral Med Oral Pathol 1984;57(6):625-30.
3. Lever WF. Inverted follicular keratosis is an irritated seborrheic keratosis. Am J Dermatopathol 1983;5(5):474.
4. Azzopardi JG, Laurini R. Inverted follicular keratosis. J Clin Pathol 1975;28(6):465-71.
5. Villaret AB, Gily B, Aga A. Inverted follicular keratosis of the nasal vestibule. Otolaryngol Head Neck Surg 2009;141(2):288-9. CrossRef
6. Ruhoy SM, Thomas D, Nuovo GJ. Multiple inverted follicular keratoses as a presenting sign of Cowden’s syndrome: case report with human papillomavirus studies. J Am Acad Dermatol 2004;51(3):411-5.
7. Soylu L, Akcali C, Aydogan LB, Ozsahinoglu C, Tuncer I. Inverted follicular keratosis. Am J Otolaryngol 1993;14(4):247-8.
8. Thom GA, Quirk CJ, Heenan PJ. Inverted follicular keratosis simulating malignant melanoma. Australas J Dermatol 2004;45(1):55-7.
9. Choi HJ, Yun SK, Kim HU, Ihm CW. Squamous eddies in irritated seborrheic keratosis. Am J Dermatopathol 2007;29(1):28-31.
10. Stierman S, Chen S, Nuovo G, Thomas J. Detection of human papillomavirus infection in trichilemmomas and verrucae using in situ hybridization. J Cutan Pathol 2010;37(1):75-80. CrossRef
11. Shih CC, Yu HS, Tung YC, Tsai KB, Cheng ST. Inverted follicular keratosis. Kaohsiung J Med Sci 2001;17(1): 50-4.
12. Roth LM, Look KY. Inverted follicular keratosis of the vulvar skin: a lesion that can be confused with squamous cell carcinoma. Int J Gynecol Pathol 2000;19(4):369-73.
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