Waldenström macroglobulinaemia presenting as tingling ulcers on the feet
Keywords:
peripheral neuropathy, storage papules, macroglobulinaemia cutisAbstract
A 56-year-old man presented with tingling ulcers on the feet. On further skin examination, papules on the knees were observed. Biopsies revealed extravascular eosinophilic deposits of IgM, and Waldenström macroglobulinaemia was diagnosed. The skin manifestations have resolved with chemotherapy. Peripheral neuropathy and storage papules are rare manifestations of Waldenström’s macroglobulinaemia.
References
1. Libow LF, Mawhinney JP, Bessinger GT. Cutaneous Waldenström’s macroglobulinemia: report of a case and overview of the spectrum of cutaneous disease. J Am Acad Dermatol. 2001; 45(6 Suppl): S202-6.
2. Abdallah-Lotf M, Bourgeois-Droin C, Perronne V, et al. Cutaneous manifestations as initial presentation of Waldenstrom’s macroglobulinemia. Eur J Dermatol. 2003;13(1):90-2.
3. Silberman J, Lonial S. Review of peripheral neuropathy in plasma cell disorders. Hematol Oncol. 2008;26(2):55-65.
4. del Olmo J, España A, Idoate MA, Panizo C. Waldenström macroglobulinemia associated with cutaneous lesions and type I cryoglobulinemia. Actas Dermosifiliogr. 2008;99(2):138-44.
5. Harnalikar M, Pande S, Kharkar V, Khopkar U. Keratotic vascular papules over the feet: a case of Waldenström’s macroglobulinaemia-associated cutaneous macroglobulinosis. Clin Exp Dermatol. 2010;35(3):278-81.
2. Abdallah-Lotf M, Bourgeois-Droin C, Perronne V, et al. Cutaneous manifestations as initial presentation of Waldenstrom’s macroglobulinemia. Eur J Dermatol. 2003;13(1):90-2.
3. Silberman J, Lonial S. Review of peripheral neuropathy in plasma cell disorders. Hematol Oncol. 2008;26(2):55-65.
4. del Olmo J, España A, Idoate MA, Panizo C. Waldenström macroglobulinemia associated with cutaneous lesions and type I cryoglobulinemia. Actas Dermosifiliogr. 2008;99(2):138-44.
5. Harnalikar M, Pande S, Kharkar V, Khopkar U. Keratotic vascular papules over the feet: a case of Waldenström’s macroglobulinaemia-associated cutaneous macroglobulinosis. Clin Exp Dermatol. 2010;35(3):278-81.
Downloads
Published
2013-07-31
Issue
Section
Observation
License
Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.
How to Cite
1.
Fischer I, Dyall-Smith D, Peters B, Stolz W, Coras-Stepanek B. Waldenström macroglobulinaemia presenting as tingling ulcers on the feet. Dermatol Pract Concept. Published online July 31, 2013:7-8. doi:10.5826/dpc.0303a03
Share
