Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report
Citation: Jegou Penouil MH, Gourhant J-Y, Segretin C, Weedon D, Rosendahl C. Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report. Dermatol Pract Concept. 2014;4(2):9. https://dx.doi.org/10.5826/dpc.0402a09
Received: September 9, 2013; Accepted: October 8, 2013; Published: April 30, 2014
Copyright: ©2014 Jegou Penouil et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Competing interests: The authors have no conflicts of interest to disclose.
All authors have contributed significantly to this publication.
Corresponding author: Cliff Rosendahl, MBBS, PhD, PO Box 734, Capalaba, Queensland, 4157Australia. Tel. +61 7 3245 3011; Fax. +61 7 3245 3022. Email: email@example.com
A case of a predominantly yellow primary superficial spreading melanoma arising on the back of a 44-year-old woman is presented. Possible causes of the clinical and dermatoscopic yellow color are discussed. Staining with the histochemical stain, Sudan Black, revealed a differential uptake compared to a closely matched control melanoma. We speculate that the clinical and dermatoscopic yellow color could be due to the presence of increased amounts of the pigment lipofuscin, which is known to produce subtle orange color in some choroidal melanomas.