A keratoacanthoma with venous invasion

A keratoacanthoma with venous invasion

Authors

  • Philipp Tschandl Department of Dermatology, Medical University of Vienna, Austria
  • Cliff Rosendahl School of Medicine, The University of Queensland, Brisbane, Australia
  • Richard Williamson Zenith Specialist Pathology, Brisbane, Australia
  • David Weedon Sullivan Nicolaides Pathology, Brisbane, Australia

Keywords:

keratoacanthoma, squamous cell carcinoma, dermatoscopy, dermoscopy, dermatopathology, venous invasion

Abstract

Keratoacanthomas are variously regarded as a self-limiting variant of squamous cell carcinoma or as a distinct benign lesion and they very seldom show attributes normally associated with malignant behaviour, such as perineural invasion. Herein we report the case of a keratoacanthoma with venous invasion proven by immunoperoxidase and elastic tissue stains.

References

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Godbolt AM, Sullivan JJ, Weedon D. Keratoacanthoma with perineural invasion: a report of 40 cases. Australas J Dermatol. 2001;42(3):168-71.

Calonje E, Jones EW. Intravascular spread of keratoacanthoma. An alarming but benign phenomenon. Am J Dermatopathol. 1992;14(5):414-7.

Weedon D. Weedon’s Skin Pathology. 3rd ed. London, England: Churchill Livingstone, 2009:702-8. CrossRef

Janecka IP, Wolff M, Crikelair GF, Cosman B. Aggressive histological features of keratoacanthoma. J Cutan Pathol. 1977;4(6):342-8.

Weedon DD, Malo J, Brooks D, Williamson R. Squamous cell carcinoma arising in keratoacanthoma: a neglected phenomenon in the elderly. Am J Dermatopathol. 2010;32(5):423-6.

Hodak E, Jones RE, Ackerman AB. Solitary keratoacanthoma is a squamous-cell carcinoma: three examples with metastases. Am J Dermatopathol. 1993;15(4):332-42; discussion 343-52.

Reed RJ. Response. Am J Dermatopathol. 1993;15(4):347-51.

Rosendahl C, Cameron A, Argenziano G, Zalaudek I, Tschandl P, Kittler H. Dermoscopy of squamous cell carcinoma and keratoacanthoma. Arch Dermatol. In press 2012.

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Published

2012-10-31

Issue

Section

Observation

How to Cite

1.
Tschandl P, Rosendahl C, Williamson R, Weedon D. A keratoacanthoma with venous invasion. Dermatol Pract Concept. Published online October 31, 2012:9-11. Accessed April 21, 2026. https://dpcj.org/index.php/dpc/article/view/dermatol-pract-concept-articleid-dp0204a03

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