Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma

Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma

Authors

  • Sarah Hocker Skin and Cancer Associates, Plantation, FL, USA
  • Harold S. Rabinovitz Department of Dermatology, University of Miami Miller School of Medicine, Miami, FL, USA
  • Margaret Oliveiro Department of Dermatology, University of Miami Miller School of Medicine, Miami, FL, USA
  • Jane Grant-Kels Department of Dermatology, University of Connecticut, Farmington, CT, USA
  • Alon Scope Department of Dermatology, Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Keywords:

dermoscopy, inverted follicular keratosis, squamous cell carcinoma, reflectance confocal microscopy

Abstract

Distinguishing between benign and malignant neoplasms of the skin is a daily challenge to dermatologists. With the use of a dermatoscope and other imaging devices, the diagnosis is often more precise. The confocal microscope is a device that uses a near-infrared laser to perform noninvasive imaging of the skin. The benefit is that the images immediately provide additional, cellular-level information that can assist in diagnosis. However, lesions may share overlapping characteristics on confocal microscopy, and hence, benign lesions can still display confocal features concerning for a cancerous process, justifying a biopsy. Here, we present a case of an inverted follicular keratosis imitating a squamous cell carcinoma on confocal microscopy.

References

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Armengot-Carbo M, Abrego A, Gonzalez T, Alarcon I, Alos L, Carrera C, et al. Inverted Follicular Keratosis: Dermoscopic and Reflectance Confocal Microscopic Features. Dermatology. 2013Aug24;227(1):62–6.

Spielvogel RL, Austin C, Ackerman AB. Inverted follicular keratosis is not a specific keratosis but a verruca vulgaris (or seborrheic keratosis with squamous eddies. Am J Dermatopathol. 1983;5(5):427-42. Am J Dermatopathol. 1983;5(5):427-42.

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Ackerman AB. Inverted Follicular Keratosis, Tricholemmoma, and Desmoplastic Tricholemmoma? In: Resolving Quandaries in Dermatology, Pathology & Dermatopathology.

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Published

2017-10-31

Issue

Section

Observation

How to Cite

1.
Hocker S, Rabinovitz HS, Oliveiro M, Grant-Kels J, Scope A. Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma . Dermatol Pract Concept. 2017;7(4):39-42. doi:10.5826/dpc.0704a09

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