Subcutaneous scalp nodule as the presenting symptom of systemic light-chain amyloidosis

Subcutaneous scalp nodule as the presenting symptom of systemic light-chain amyloidosis

Authors

  • Joseph Tadros University of Cincinnati College of Medicine
  • Stacey Goodman Vanderbilt University Medical Center, Department of Medicine
  • Eric R. Tkaczyk Vanderbilt University Medical Center, Department of Dermatology

Keywords:

nodular amyloidosis, systemic AL amyloidosis, pilar cyst, subcutaneous nodule

Abstract

We present a case of subcutaneous nodular amyloidosis mimicking a pilar cyst. Further evaluation led to the diagnosis of malignant systemic light-chain amyloidosis. The epidemiology and histopathological features of light-chain amyloidosis with cutaneous involvement are reviewed, as well as current recommendations for initial evaluation.

Author Biographies

Joseph Tadros, University of Cincinnati College of Medicine

Medical Student

Stacey Goodman, Vanderbilt University Medical Center, Department of Medicine

Professor of Medicine, Department of Hematology and Oncology

Eric R. Tkaczyk, Vanderbilt University Medical Center, Department of Dermatology

Assistant Professor of Dermatology

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Published

2018-07-31

Issue

2018 Vol 8, No 3 | July

Section

Observation

License

Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.

How to Cite

1.
Tadros J, Goodman S, Tkaczyk ER. Subcutaneous scalp nodule as the presenting symptom of systemic light-chain amyloidosis. Dermatol Pract Concept. 2018;8(3). Accessed June 25, 2026. https://dpcj.org/index.php/dpc/article/view/dermatol-pract-concept-articleid-dp0803a07

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